The complex process of rainfall-runoff relationship in each catchment area is controlled by numerous known and often unknown factors in the time and place dimension. One of these factors is precipitation. Precipitation is the most important atmospheric phenomenon that is directly affect the hydrological cycle, especially in discharge changes. In this study, in order toinvestigate the relation between rainfall and runoff and investigating their temporal and spatial variation, the daily precipitation data of 160 synoptic and rain gage stations and 12 hydrometric stations with different statistical period were used for 12 sub basins in Karun. Linear and nonlinear correlation equations between the two elements were calculated. In the final stage, cumulative coefficients of precipitation and runoff and its temporal-spatial correlation were calculated.The results showed that nonlinear transformations did not affect the relation between precipitation and runoff and the relation between the two elements is linear. The height, type of precipitation and temperature affected different influences on the correlation between rainfall and runoff. Also it has been shown that the physical properties of the basin, especially tectonic plates, and the impact of human factors, especially dam construction and water transport, have a great impact on the relationship between them.